Spin interference in silicon one-dimensional rings

We present the first findings of the spin transistor effect caused by the Rashba gate-controlled ring embedded in the p-type self-assembled silicon quantum well that is prepared on the Si (100) surface. The coherence and phase sensitivity of the spin-dependent transport of holes are studied by varying the value of the external magnetic field and the gate voltage that are perpendicular to the plane of the double-slit ring. Firstly, the quantum scatterers connected to two one-dimensional leads and the quantum point contact inserted in the one of the arms of the double-slit ring are shown to define the amplitude and the phase of the Aharonov-Bohm and the Aharonov-Casher conductance oscillations. Secondly, the amplitude and phase sensitivity of the 0.7 feature of the hole quantum conductance staircase revealed by the quantum point contact inserted are found to result from the interplay of the spontaneous spin polarization and the Rashba spin-orbit interaction.Comment: 2 pages, 2 figures, presented at the 5th International Conference on Strongly Correlated Electron Systems, SCES'05, Vienna, Austria, 26-30 July, 200

Space-Borne Radio-Sounding Investigations Facilitated by the Virtual Wave Observatory (VWO)

The goal of the Virtual Wave Observatory (VWO) is to provide userfriendly access to heliophysics wave data. While the VWO initially emphasized the vast quantity of wave data obtained from passive receivers, the VWO infrastructure can also be used to access active sounder data sets. Here we use examples from some half-million Alouette-2, ISIS-1, and ISIS-2 digital topside-sounder ionograms to demonstrate the desirability of such access to the actual ionograms for investigations of both natural and sounder-stimulated plasma-wave phenomena. By this demonstration, we wish to encourage investigators to make other valuable space-borne sounder data sets accessible via the VWO

Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216

Feedback Neural Networks For Artist Ionogram Processing

Modern pattern recognition techniques are applied to achieve high quality automatic processing of Digisonde ionograms. An artificial neural network (ANN) was found to be a promising technique for ionospheric echo tracing. A modified rotor model was tested to construct the Hopfield ANN with the mean field theory updating scheme. Tests of the models against various ionospheric data showed that the modified rotor model gives good results where conventional tracing techniques have difficulties. Use of the ANN made it possible to implement a robust scheme of trace interpretation that considers local trace inclination angles available after ANN completes tracing. The interpretation scheme features a new algorithm for ƒ0F1 identification that estimates an α angle for the trace segments in the vicinity of the critical frequency ƒ0F1. First results from off-line tests suggest the potential of implementing new operational autoscaling software in the worldwide Digisonde network

Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α

Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling through the estrogen receptor α (ERα). Moreover, in vivo and in vitro experiments revealed the estrogen-like effects of TPP-based compounds. Here, we tested the hypothesis that TPP-based compounds regulate the activity of ERα. Methods We used ERa-positive and ERα-negative human breast adenocarcinoma cell lines (MCF-7 and MDA-MB-231, respectively). Cell proliferation was measured using a resazurin cell growth assay and a real-time cell analyzer assay. Cell cycle progression was analyzed using flow cytometry. Real-time PCR was used to assess mRNA expression of endogenous estrogen-responsive genes. Luciferase activity was measured to evaluate transcription driven by estrogen-responsive promoters in cells transfected with an estrogen response element (ERE)3-luciferase expression vector. Results The TPP-based molecules SkQ1 and C12TPP, as well as the rhodamine-based SkQR1, did not increase the proliferation or alter the cell cycle progression of MCF-7 cells. In contrast, 17β estradiol increased the proliferation of MCF-7 cells and the proportion of cells in the S/G2/M-phases of the cell cycle. TPP-based compounds did not affect the induction of transcription of an ERE-luciferase expression vector in vitro, and SkQ1 did not alter the levels of expression of estrogen-dependent genes encoding GREB1, TFF1, COX6, and IGFBP4. Conclusion TPP-based compounds do not possess properties typical of ERα agonists

The Nature of Ferromagnetism in a System of Self-Ordered α-FeSi₂ Nanorods on a Si(111)-4° Vicinal Surface: Experiment and Theory

In this study, the appearance of magnetic moments and ferromagnetism in nanostructures of non-magnetic materials based on silicon and transition metals (such as iron) was considered experimentally and theoretically. An analysis of the related literature shows that for a monolayer iron coating on a vicinal silicon surface with (111) orientation after solid-phase annealing at 450–550 °C, self-ordered two-dimensional islands of α-FeSi2 displaying superparamagnetic properties are formed. We studied the transition to ferromagnetic properties in a system of α-FeSi2 nanorods (NRs) in the temperature range of 2–300 K with an increase in the iron coverage to 5.22 monolayers. The structure of the NRs was verified along with distortions in their lattice parameters due to heteroepitaxial growth. The formation of single-domain grains in α-FeSi2 NRs with a cross-section of 6.6 × 30 nm2 was confirmed by low-temperature and field studies and FORC (first-order magnetization reversal curves) diagrams. A mechanism for maintaining ferromagnetic properties is proposed. Ab initio calculations in freestanding α-FeSi2 nanowires revealed the formation of magnetic moments for some surface Fe atoms only at specific facets. The difference in the averaged magnetic moments between theory and experiments can confirm the presence of possible contributions from defects on the surface of the NRs and in the bulk of the α-FeSi2 NR crystal lattice. The formed α-FeSi2 NRs with ferromagnetic properties up to 300 K are crucial for spintronic device development within planar silicon technology

Longitudinal variation in the ionosphere-plasmasphere system at the minimum of solar and geomagnetic activity: Investigation of temporal and latitudinal dependences

International audienceWe use the Global Self-consistent Model of the Thermosphere, Ionosphere and Protonosphere (GSM TIP) as the first-principle calculation of the physical system state, the quick-run ionospheric electron density model (NeQuick) as the climatology background, and the International Reference Ionosphere-based Real-Time Assimilative Model for a global view of the ionospheric weather during a quiet period of the December 2009 solstice. The model computations are compared to the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) radio occultation profiles, CHAMP and Gravity Recovery and Climate Experiment in situ densities, and GPS total electron content (TEC). It is shown that the plasma density in the ionosphere is generally larger in the American/Atlantic longitudinal sector at any local time. The high-latitude density enhancements are visible in the GSM TIP output at different altitudes but are not reproduced by the NeQuick empirical model. Given that observational data confirm an existence of the high-latitude areas where ionospheric densities are elevated in the altitude range between 300 and 480 km, we conclude that the NmF2 maximum in the GSM TIP output can be trusted. Indeed, such high-latitude NmF2, ionospheric electron content, and TEC maxima in the American longitude sector form on the proper places as shown by the GSM TIP data, COSMIC and GPS observations. According to our results, the high-latitude maximum of NmF2 (1) manifests itself only when the integration over LT or UT of the global maps for 22 December 2009 includes nighttime, i.e., supporting an argument of its close association with the Weddell Sea Anomaly, and (2) also appears in the Ne distribution at altitudes above the F2 peak

Mitochondria-Targeted Antioxidant SkQ1 Prevents the Development of Experimental Colitis in Mice and Impairment of the Barrier Function of the Intestinal Epithelium

Mitochondria-targeted antioxidants have become promising candidates for the therapy of various pathologies. The mitochondria-targeted antioxidant SkQ1, which is a derivative of plastoquinone, has been successfully used in preclinical studies for the treatment of cardiovascular and renal diseases, and has demonstrated anti-inflammatory activity in a number of inflammatory disease models. The present work aimed to investigate the therapeutic potential of SkQ1 and C12TPP, the analog of SkQ1 lacking the antioxidant quinone moiety, in the prevention of sodium dextran sulfate (DSS) experimental colitis and impairment of the barrier function of the intestinal epithelium in mice. DSS-treated animals exhibited weight loss, bloody stool, dysfunction of the intestinal epithelium barrier (which was observed using FITC-dextran permeability), reduced colon length, and histopathological changes in the colon mucosa. SkQ1 prevented the development of clinical and histological changes in DSS-treated mice. SkQ1 also reduced mRNA expression of pro-inflammatory molecules TNF, IL-6, IL-1β, and ICAM-1 in the proximal colon compared with DSS-treated animals. SkQ1 prevented DSS-induced tight junction disassembly in Caco-2 cells. Pretreatment of mice by C12TPP did not protect against DSS-induced colitis. Furthermore, C12TPP did not prevent DSS-induced tight junction disassembly in Caco-2 cells. Our results suggest that SkQ1 may be a promising therapeutic agent for the treatment of inflammatory bowel diseases, in particular ulcerative colitis

Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

A new mitochondria-targeted probe MitoCLox was designed as a starting compound for a series of probes sensitive to cardiolipin (CL) peroxidation. Fluorescence microscopy reported selective accumulation of MitoCLox in mitochondria of diverse living cell cultures and its oxidation under stress conditions, particularly those known to cause a selective cardiolipin oxidation. Ratiometric fluorescence measurements using flow cytometry showed a remarkable dependence of the MitoCLox dynamic range on the oxidation of the sample. Specifically, MitoCLox oxidation was induced by low doses of hydrogen peroxide or organic hydroperoxide. The mitochondria-targeted antioxidant 10-(6-plastoquinonyl)decyltriphenyl-phosphonium (SkQ1), which was shown earlier to selectively protect cardiolipin from oxidation, prevented hydrogen peroxide-induced MitoCLox oxidation in the cells. Concurrent tracing of MitoCLox oxidation and membrane potential changes in response to hydrogen peroxide addition showed that the oxidation of MitoCLox started without a delay and was complete during the first hour, whereas the membrane potential started to decay after 40 minutes of incubation. Hence, MitoCLox could be used for splitting the cell response to oxidative stress into separate steps. Application of MitoCLox revealed heterogeneity of the mitochondrial population; in living endothelial cells, a fraction of small, rounded mitochondria with an increased level of lipid peroxidation were detected near the nucleus. In addition, the MitoCLox staining revealed a specific fraction of cells with an increased level of oxidized lipids also in the culture of human myoblasts. The fraction of such cells increased in high-density cultures. These specific conditions correspond to the initiation of spontaneous myogenesis in vitro, which indicates that oxidation may precede the onset of myogenic differentiation. These data point to a possible participation of oxidized CL in cell signalling and differentiation